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HDL-CHigh Density Lipoprotein-Cholesterol
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Decreased HDL-C levels are often associated with increased atherosclerotic cardiovascular disease (ASCVD) risk.
The study, which pooled six population-based cohorts in the United States, included 31,843 adults for whom there were baseline HDL-C levels and at least two longitudinally collected spirometry readings.
The criteria consist of 5 components of MetS namely abdominal obesity (Waist circumference in males >102cm and in females >88cm), raised TG (>150mg/dl], low HDL-C (in males <40mg/dl and in females <50mg/dl], raised blood pressure ([greater than or equal to] 130/85mmHg] and impaired blood glucose ([greater than or equal to] 110mg/dl].
In men, HDL-C levels correlated directly with 4-minute fast walking speed, 400-meter walking speed, and knee-extension torque, the report indicates, whereas in women, HDL-C levels correlated significantly only with knee extension torque.
9%) of the initial Seralyzer HDL-C measures were within [+ or -] 0.
Furthermore, people with Tangier disease [who lack ATP-binding cassette transporter 1 (ABCA1), a key first step in cholesterol export from cells] have very low HDL-C concentrations and accumulate cholesterol-laden macrophages in many different tissues (10, 11).
Although epidemiologic studies have shown that low HDL-C is a negative risk factor, raising HDL-C pharmacologically has not been definitively established to protect against ischemic heart disease (IHD) (5, 7).
We analyzed a specimen from a 69-year-old man, using a direct HDL-C assay, and obtained a value that was less than the 40 mg/L detection limit of the assay.