HDL2cHigh Density Lipoprotein 2 Cholesterol
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The following variables did not have a significant correlation with PCSK9: total cholesterol, LDL particle concentration, high-density lipoprotein (HDL), HDL2, HDL3, HDL2A, HDL2B, HDL2C, HDL3A, HDL3B, pro B-type natriuretic peptide, 1,5-anhydroglucitol (GlycoMark), apolipoprotein B, triglycerides, systolic blood pressure, diastolic blood pressure, height, weight, and body mass index.
Subsequently, these authors (8) demonstrated that the increase in HDL-C seen with niacin therapy can result from a reduction in catabolism, an increase in the expression of ABC1 transporter, or an enhancement in the conversion of HDL3 to HDL2C by the phospholipids transfer proteins lecithin: cholesterol acyltransferase and lipoprotein lipase (4,13).