After menopause, TC and LDLc usually increase and these changes are accompanied by a decrease in HDLc
and an increase in TG.
We considered a subject to have MS in three or more of the following cases: (i) blood pressure [greater than or equal to]130/85 mmHg or the subject was taking antihypertensive medications; (ii) waist circumference [greater than or equal to]80 cm in women and [greater than or equal to]90 cm in men; (iii) serum triglyceride [greater than or equal to]150 mg/dL (1.69 mmol/L); (iv) HDLC
level <50 mg/dL (1.29 mmol/L) in women or <40 mg/dL (1.03 mmol/L) in men; or (v) fasting glucose [greater than or equal to]110 mg/dL (6.1 mmol/L) or verified diagnosis of type 2 diabetes.
However, the mean age, BMI, SBP, DBP, TC, TGs, HDLc
, LDLc, blood glucose, cigarette smoking habit, and drinking habit differed significantly between the two study groups (P< 0.05; Table 1).
Group Statistics Showing the Mean/SEM of the Lipid Parameters in Different Study Groups SH OH Control Total Cholesterol 183/4.9 206/6.9 162/1.9 Mean/SEM LDLc Mean/SEM 96.2/3.7 98/2.8 87.6/2.6 HDLc
Mean/SEM 46.9/0.9 43.7/0.77 50.3/1.3 Triglyceride 117.6/8.4 167/13.1 112/1.9 Mean/SEM Table 2.
nonHDLc was calculated as total cholesterol (TC) minus HDLc
. apo B was measured with immunoturbidometric technique on the Hitachi 917 analyzer (Roche Diagnostics), using reagents and calibrators from Wako Chemicals.
and APOA1 levels were also evaluated and no statistically significant differences were found for any of the polymorphisms.
On univariate analysis, the following were factors significantly associated with death in acute stroke patients: history of DM, smoking, alcohol abuse, dyslipidemia, atrial fibrillation, cardiomyopathy (CHF), CKD, hemorrhagic stroke type, hyperglycemia, low HDLc
, increased triglycerides, high TG, hyperuricemia, GCS less than 9, NIHSS > 14, mRS > 2, and presence of in-hospital complications (p < 0.05).
The levels of fast serum glucose (FSG), insulin (FINS), and serum lipids including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDLC
), and low-density lipoprotein cholesterol (LDLC) and liver function indexes including serum glutamic-pyruvic transaminase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) were quantified separately with commercial kits (Beijing Leadman Biochemical Co.
Serum TC, TAG, and HDLc
were determined as described in commercial kits (Randox Laboratories Ltd., Antrim, UK).
The serum samples were analyzed for total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDLC) and high density lipoprotein cholesterol (HDLC
) using corresponding commercial kits (Nanjing Jiancheng Bioengineering Institute, Nanjing, China) according to manufacturer recommended procedures.