We are looking for a contract manufacturer (CMO) for preparatory project work towards GMP-compliant manufacture of a recombinant VLP derived from HEK293
Among 17 human different cell types (A172, Daoy, HEK293
, HeLa, HepG2, MCF-7, NT2, 5637, 1321N1, NCCIT, Jurkat, Y79, HS5, PC3, Raji, OVCAR3 and A549), OCT4B3 transcript was detected just in 1321N1 and 5637 cell lines (Figure 4).
A, confocal microscopy immunofluorescence of HEK293
cells transfected with mCherry-tagged claudin-3 together with various GFP-tagged constructs.
To determine the cytotoxic effects in various tumor cells, 20 [micro]m of compound 1 was used to treat six different human cell lines, including SW620 (human gastric cancer), MCF-7 (human breast cancer), T98G (human glioblasma), T24, T24R2, and HEK293
(Human Embryonic Kidney 293) cell lines.
These aggregates, which may show remarkable differences regarding their Z potential and are detectable by dynamic light scattering , show markedly different capacities to activate TLR4 and downstream pro-inflammatory NF-K[beta] signaling pathways in engineered HEK293
The inhibitory effects of carvacrol on TRPM7 and TRPM7-like currents in HEK293
cells and glioblastoma cell line were further confirmed .
We used HEK293
cells transfected with Epac FRET probe to optimize our hyperspectral imaging and analysis approaches and to design automated cell analysis techniques to determine the subcellular localization of FRET signals.
have demonstrated that both LOCM and IOCM caused a marked increase in caspases-3 and -9 activities and poly(ADP-ribose) polymerase fragmentation in HEK293
cells; no effect was observed by them on caspase-8 and -10, thus indicating that the RCM activated apoptosis mainly through the intrinsic pathway .
MEK are upstream regulators of mTOR, and can mediate amino acid signal-induced phosphorylation of S6K1 in HEK293
cells (Casas-Terradellas et al.
Polarized cells, either differentiated (for example, Caco-2 cells) or transfected with the transporters of interest (such as MDCKII, HEK293
, LLCPK cells) are often used to characterize efflux drug transporter interactions.
Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor b in HEK293
En el caso particular del uso de la linea celular HEK293
para la produccion de vacunas contra el virus de Influenza, Le Ru A.