4, HFHC induced significant increase in body weight compared to the normal control group (p < 0.
HFHC diet caused a significant increase in cholesterol content in feces (p < 0.
5, HFHC diet induced significant decrease in HMGR mRNA and protein expression (p < 0.
6, jatrorrhizine obviously and dose-dependently raised the mRNA expression of LDLR, which was almost 3-fold higher than that of HFHC group (p < 0.
7, jatrorrhizine can improve expression of mRNA and protein level of CYP7A1, compared with HFHC group.
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