HFSRHand-Foot Skin Reaction
HFSRHeavy Fraction of Sarcoplasmic Reticulum
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References in periodicals archive ?
Treatment with sorafenib alone is tolerated, but AEs including HFSR, rash and liver failure occur more frequently in patients with HCC than those in patients from other geographic regions (Ogasawara et al., 2011).
(28) reviewed the sorafenib arm in the phase III TARGET study and could detect rash/ desquamation in 51%, of patients, HFSR in 49% of patients and alopecia in 39% of cases.
The term hand-foot skin reaction (HFSR) refers to a group of signs and symptoms that can affect the hands and/or feet of patients receiving sorafenib and sunitinib; these symptoms may occur simultaneously or sequentially in a high percentage of patients.