9,10) Both BRCA1/2 mutation-positive and sporadic cases of nonuterine HGSC
have been shown to be associated with concomitant STIC, with matched pairs of STIC-HGSC
harboring identical TP53 mutations.
Findings demonstrated that in the 48 HGSC
patients with STIC, IMP3 was positive in 46% of STIC lesions and had a similar positive rate in the invasive components of HGSC
(Hour Glass Supply Chain) is an e-supply chain structured like an hour glass, with customers at the top and grassroots suppliers at the bottom, see Figure 5.
120,124,128) A prototypic HGSC
is WT1 (+), ARID1A (+), and p53 (+, strong, diffuse).
Exhibit 2 also shows the average annual rates of return during the period January 1980 to December 1990 for each of the market size deciles, the FTA and the HGSC
Indexes, as well as a specially constructed All Share Equally Weighted (ASEW) Index.
1) is the assembly produced by the HGSC
(human genome sequencing center) at the Baylor College of Medicine.