HIV-IHuman Immunodeficiency Virus Type-I
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One of the modifications which is of importance in HTLV-I/HIV-I coinfection is the modulation of CCR5 expression rate which is one of the co-receptors helping HIV-I's entry into the cells (21).
HIV-I and HIV-2 are believed to be the result of cross .species transmission from simian immunodeficiency virus (SIV)-infected chimpanzees and sooty mangabeys, respectively, which represent 2 (SIVcpz and SIVsm) of the 6 major lentiviral phylogenetic lineages (1,2).