HLGRHigh-Level Gentamicin Resistance (chemotherapy)
HLGRHarrang Long Gary Rudnick P.C. (Oregon)
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faecium) exhibited HLAR (both HLGR and HLSR) and 5 (6.3% isolates exhibited HLGR alone.
(15) In addition, a 120-[micro]g gentamicin disc was used to identify HLGR. In the disc diffusion method, the discs were placed on the agar medium before they were incubated at 37 [degrees]C for 24 hours, and the diameter of the zone of inhibition was measured.
MIC of HLGR and HLSR enterococcal isolates was determined by E-test (Epsilometer Test; 0.064-1024 [micro]g/ml) (as shown in Figure 3).
aureus (n=148) (n=28) (n=3) Linezolid 0 0 0 Vancomycin 0 3,6 0 Teicoplanin 22.3 3,6 0 TMP/SMX 41.9 N/A 33.3 Clindamycin 73 N/A 0 Erythromycin 89.9 N/A 66.7 Methicillin 89.2 N/A 33.3 Ciprofloxacin 58.8 N/A 0 Ampicillin N/A 6 N/A Gentamicin 98 N/A 0 HLGR N/A 67.9 N/A HLSR N/A 67.9 N/A CNS: coagulase-negative staphylococcus; TMP/SMX: trimethoprim + sul-famethoxazole; HLGR: High-level gentamicin resistance; HLSR: High-levelstreptomycin resistance Table 3.
[9] Identification of enterococcal species and their antibiotic resistance pattern with respect to HLGR and VRE were taken to concern in this pilot study.
The disk diffusion method and minimum inhibitory concentration (MIC) test were performed by using Mueller Hinton agar and Brain Heart Infusion agar for detection of HLGR isolates among 180 enterococcus species according to the Clinical and Laboratory Standards Institute (CLSI 2014) recommendation (11).
The aim of this study was to determine the susceptibility to different groups of antibiotics and the frequency of occurrence of HLAR, HLGR, and HLSR phenotypes among E.
A total of 129/178 (72.47%) high level aminoglycoside resistant enterococci (HLGR and HLSR) were observed among our study isolates.
HLGR ST16 isolates recovered from 2 IE patients during the study period have been characterized (3) and were excluded from the present study.
Patient A, an 81-year-old man with a previous stroke and a urinary catheter, was admitted twice within 1 month with HLGR E.