HMOXHeme Oxygenase
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2005) 2 Induction of alterations in gene expression: Decrease in E-cadherin Activation of JNK, increased HEF1, also known as NEDD9 and CAS-L 2 HMOX CASP-3 VEGF-MMPs- IL-8 CXCL 10, CXCL11 2 SIRT family (Huang et al.
In this type of renal cancer, we predicted that using a drug that would specifically inhibit the enzyme HMOX, involved in Heme metabolism, would selectively and efficiently kill cancer cells, leaving normal cells intact," explained Ruppin.
They identified variants in two genes, TGFB2 and HMOX that appear to contribute to the development of CM in Angolan children.