HMW2High Molecular Weight Component
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Conservation and diversity of HMW1 and HMW2 adhesin binding domains among invasive nontypeable Haemophilus influenzae isolates.
The unimodal polyethylenes, HMW2, HMW3 and LMW, were provided by Borealis A/S.
Given the dichotomy among nontypable strains expressing either HMW or Hia-like adhesins and the serologic conservation at least among the HMW1 and HMW2 proteins, a vaccine based on a combination of such proteins may be protective against disease caused by most nontypable H.