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Also, some reliable markers in the development of the pancreatic [beta] cells including PDX-1, islet-1, Nkx6.1, and HNF6 were expressed higher on day 21 compared to day 14 and the undifferentiated iPSCs (Figures 9(c)-9(f)).
HNF6 directly activates the proendocrine transcription factor and is significant for endocrine differentiation .
Gannon, "The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors," Diabetes/Metabolism Research and Reviews, vol.
We evaluated hepatic expression of CYP2C and CYP3A isoforms in connection with the changes of liver-enriched transcription factors: HNF4[alpha], HNF6, STAT5b (signal transducer and activator of transcription 5b) and PXR receptor, and GH secretory pattern.
Characteristics of changes in HNF6 mRNA expression were very similar to those observed in the case of HNF4[alpha].
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- HNF-3/fork head-like protein 5
- HNF-3/fork-head homolog 3
- HNF-3/fork-head homolog-3
- HNF-3/forkhead homolog 11
- HNF1 beta A
- HNF1 homeobox B
- HNF3/FH transcription factor genesis