HPAIVHighly Pathogenic Avian IV (virology)
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The A/goose/Hungary/1030/2017 H5N8 HPAIV (HA clade, isolated during the recent 2016-2017 epidemic of HPAI in Hungary, obtained from the virus repository of National Food Chain Safety Office Veterinary Diagnostic Directorate (NFCSO-VDD), Budapest, Hungary, was used in this study.
This virus subsequently was the predominant strain during HPAIV outbreaks among poultry in the United States in 2015, particularly during March-June (9,10), and was detected in wild birds migrating along the Pacific, Central, and Mississippi flyways (11,12).
layers, breeders and broilers), poultry production system categories, age of birds and incidence rates of morbidity, mortality, case fatality and culling rate in commercial poultry farm chickens infected with HPAIV (H5N1).Whereas Figure 1 portrays the spatial allocation of the different chicken farms infected in the study area belonging to FAO poultry production system 2 and 3.
Keywords: Pathogenicity, highly pathogenic avian influenza virus (HPAIV), H5N1, SPF ducks, wild birds.
Enhanced surveillance in wild birds is needed for early detection of new introductions of HPAIV and to trace the transmission route of HPAIV.
Due to this unique characteristic, the viruses are further classified into two types known as a highly pathogenic avian influenza virus (HPAIV) and a low pathogenic avian influenza virus (LPAIV) (Capua and Alexander, 2004).
We classified Dk/Tw/17 as an HPAIV on the basis of the amino acid sequence at the hemagglutinin cleavage site (PLRERRRKR/G) and its high lethality in chickens (intravenous pathogenicity index 3.0).
A virus that causes no or mild disease in chickens is considered a low pathogenicity avian influenza virus (LPAIV); a virus that causes high rates of death in chickens is considered a highly pathogenic avian influenza virus (HPAIV) (4).
Occasionally, transmission of a highly pathogenic avian influenza virus (HPAIV) from infected poultry to humans results in a severe public health crisis (1).
We report detection of an H5N6 subtype HPAIV in a fecal sample obtained from a wild bird sampled in South Korea during the fall 2016.
Transcontinental spread of these strains and an earlier HPAI virus (HPAIV) of the goose/Guangdong lineage of subtype H5N1 has been linked to dissemination by migratory wild birds (4).