As will be discussed in more detail below, according to the Directorate, the reason why the manufacture and sale of sNA should not be (and are not) regulated under the HPTA and HPTR is, in a nutshell, that sNA is not (at least generally speaking) inherently risky, either as a chemical substance or as a genetic element.
In Section II, this paper describes the regulation of human pathogens under the HPTA, including that the manufacture and sale of sNA is not, generally, directly regulated.
(29) According to the Directorate: "Canadian legislation provides a web of regulation that targets, from cradle to grave, the key risk concerns across multiple points of intervention: from the researcher to the raw materials to the laboratory to the commercialization and disposal coverage, ensuring that there are few gaps that could pose a risk." (30) The key act that regulates human biosafety and security is the HPTA. (31) However, neither synthetic biology nor sNA are explicitly mentioned in the HPTA or the HPTR.
While neither synthetic biology nor sNA is explicitly mentioned in the HPTA nor the HPTR, the Directorate states: "Existing legislation is sufficiently broad to apply to the manufacture of synthetic DNA and the activities surrounding it including storage, disposal, release etc." (38) Elsewhere in the same document, it qualifies that claim, saying that "[i]n most cases definitions or "triggers" under key legislation ...
papaya seed extracts at 72 hpta
. Apparently, tail malformation was observed in embryos at 0.03% (for mature seed) and 0.1% (for young seed) or higher concentrations which indicate concentration dependent.
We found even larger correlations between HPTA and consonant group thresholds (group A: r = -0.64, p < 0.001; group B: r = -0.70,p < 0.001; group C: r = -0.71,p < 0.001).
Further analysis showed that SeRTs were only weakly correlated with audiometric thresholds: HINT thresholds did not correlate with either LPTA (r = 0.17) or HPTA (r = 0.07), while QuickSIN thresholds correlated weakly with the LPTA (r = 0.31, p < 0.05) but not significantly with the HPTA (r = 0.22, p < 0.3).
We performed further analyses of the effects of age on SeRTs after factoring out the contributions of LPTA, HPTA, and group A and group B consonant identification performance.
Despite the presence of small but significant age-related elevations in LPTA, HPTA, and CaST thresholds, experiment 2 failed to find significant age-related changes in SeRTs measured with either the QuickSIN or HINT.
To highlight that attribute HPTA
is promoting the product with the slogans "taste zero zinc" and "no metallic aftertaste."
has positioned CoughPops as a natural alternative to unpleasant-tasting cough syrups and drying decongestants and analgesics, all of which executives say have the potential to produce significant adverse reactions and side effects.
To emphasize that feature HPTA
has trademarked the phrases "taste zero zinc" and "no metallic aftertaste."