HS27Heat Shock Protein 27 kDa
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Abbreviations: MDR, multidrug resistance; POM, pivaloxymethyl; Pgp, P-glycoprotein; PBS, phosphate buffered saline; DMSO, dimethylsulfoxide; RPMI-1640 medium, Roswell Park Memorial Institute-1640 medium; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FBS, fetal bovine serum; HS27, human diploid fibroblast cell line; HPLC, high performance liquid chromatography; UV, ultraviolet; MALD1-TOF MS, matrix-assisted laser desorption/ionization timeof-flight mass spectrometry; DOX, doxorubicin; ATP, adenosine triphosphate; ATPases, ATP hydrolases; TMD, transmembrane domain; NBD, nucleotide binding domain; Rh-123, rhodamine 123; Q, quercetin; Q-glu, quercetin glucuronide; Q-sul, quercetin sulfate; DIC, differential interference contrast.
One can see his character in pieces such as HS27 and HS37.
Because we were able to detect characteristic changes in HS27 phosphorylation induced by arsenite (32,40), it is clear that our experimental system has the sensitivity to detect a change in HSP27 isoform pattern if one were elicited by EMF exposure.