References in periodicals archive ?
The activity of HTGL in the plasma samples was measured as described previously (26).
Although EL has a 44% and 41% amino acid sequence homology with LPL and HTGL (10), the cross-reactivity of this ELISA against human LPL and HTGL was <0.1% (Fig.
3, A and B), in contrast to the marked heparin-releasable HTGL activity in the same samples (Fig.
These differences have resulted in confusion as to whether the plasma concentration of EL is really higher than the concentrations of LPL and HTGL without heparin infusion.
It has been reported that EL forms a head-to-tail dimer in the human plasma, and the homodimer formation is essential for the maintenance of EL activity (36), as is the case with LPL and HTGL. In addition, EL is proteolytically processed into 40- and 28-kDa fragments and inactivated by proprotein convertases (37).
 Nonstandard abbreviations: CHD, coronary heart disease; ERT, estrogen replacement therapy; LDL-C, LDL-cholesterol; HDL-C, HDL-cholesterol; ape, apolipoprotein; LRP, LDL-related receptor protein; HRT, hormone replacement therapy; BMI, body mass index; NMAPS, New Mexico Aging Process Study; NMMRL, New Mexico Medical Reference Laboratory; CNL, Clinical Nutrition Laboratory; LPL, lipoprotein lipase; HTGL, hepatic lipase; and IDL, intermediate-density lipoprotein.
Acronyms browser ?
Full browser ?