HTLV-2Human T Cell Leukemia Virus type 2
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Accordingly, if GD21 and rgp46-1 were positive, the samples were reported as positive HTLV-1 and if GD21 and rgp46-2 were positive, the samples were reported as positive HTLV-2. Positive bands p19, p24 and GD21 without the presence of specific bands type rgp46-1 and rgp46-2 also were considered as positive HTLV.
O HTLV-2 esta associado a leucemia de celulas pilosas, a eritrodermatite, a polineuropatias e, em coinfectados com HIV, a infeccoes bacterianas e micoses fungoides.
Since its discovery in 1979 three additional human deltaretroviruses (HTLV-2, HTLV-3 and HTLV-4) have been found, but only HTLV-1 and HTLV-2 have so far been associated with human disease.
HTLV-2 seems to have less pathogenicity, although there are reports of association with neurological diseases similar to HAM/TSP (4).
HTLV-2 is less pathogenic but is thought to cause similar neurologic illnesses and increase susceptibility to opportunistic infection.
HTLV-2 has been linked to the T-cell variant of hairy-cell leukemia that also strikes adults.
While HTLV-2 can also cause neurological disease, it appears to be less common than HTLV-1 infection in Lima (18, 19).
(2) It was then believed that HTLV-2 could be associated with hairy cell leukemia.
From 1995 through 1998, donors were screened for antibodies against HTLV-1 and HTLV-2 by standard ELISA (Abbott HTLV-1/HTLV-2 enzyme immunoassay; Abbott Laboratories, Abbott Park, IL, USA).
PTLV-1, PTLV-2, and PTLV-3 include human (HTLV-1, HTLV-2, and HTLV-3) and simian (STLV-1, STLV-2, and STLV-3) viruses (1-6).