HTR3Histidine Transport Regulator-3 (protein)
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The HTR3 receptors are postsynaptic and ionotropic, activated by ligands, allowing the flow of sodium ([Na.sup.+]) ions; (d) inactivation: once recaptured, the serotonin is inactivated by monoamine oxidase (MAO) enzymes, generating 5hydroxyindoleacetic acid (5-HIAA); (e) presynaptic stimulation: HTR1B and HTR1D receptors modulate the liberation of serotonin.
They found that three HTR3 variants were significantly associated with the effectiveness of ondansetron treatment for alcohol dependence.
HTR3: Poor performing organizations are less likely to change their domain by adding new services than are other organizations.