HDT

(redirected from Highest Dose Tested)
AcronymDefinition
HDTHigh Dose Therapy
HDTHaus der Technik (German: The Art House)
HDTHead-Down Tilt
HDTHeat Deflection Temperature (plastics)
HDTHigh Design Technology
HDTHeavy Duty Truck
HDTHeavy Duty Tire
HDTHard Disk Toolkit
HDTHeatpipe Direct Touch (Xigmatek)
HDTHeat Distortion Temperature (plastics)
HDTHighest Dose Tested (EPA)
HDTHenry David Thoreau
HDTHeavy-Duty Truck
HDTHardware Detection Tool (software)
HDTHost Digital Terminal
HDTHospitalisation à la Demande d'Un Tiers (French)
HDTHolden Dealer Team
HDTHeader-Dictionary-Triples (resource description framework)
HDTHelp Desk Ticket (various organizations)
HDTHydrotreater (oil refinery)
HDTHorse Driving Trials
HDTHigh Definition Traffic (TomTom; Netherlands)
HDTHigh Density Tape
HDTHawaiian Daylight Time
HDTHasse Diagram Technique
HDTHuron Daily Tribune (Bad Axe, MI, USA)
HDTHardware Debug Tool (AMD)
HDTHigh Resolution Dipmeter Tool (Schlumberger, borehole analysis)
HDTHazardous Devices Team
HDTHelmet Drop Tower
HDTHybrid Discretionary Trust
HDTHot Dogger Tours (Brea, CA)
HDTHandoff Detection Time
HDTHazardous Device Technician
HDTHosted Data Translation (Edict Systems)
HDTHospital Dying Trajectory
HDTHarmonic Drive Technologies
HDTHemodialysis Treatment
HDTHalo Dream Team (gaming)
HDTHoliday Double Time (pay)
HDTHot Deck Temperature
HDTHomeland Defense Training
References in periodicals archive ?
Based on safety and immunogenicity, the highest dose tested in Part A, 10 -microg, has been selected as the optimal dose level to test in Part B of the study.
The highest dose tested, 20mg, achieved clinically meaningful improvements throughout the study over baseline and placebo with a maximum improvement of 29.1 mmHg, consistent with the interim analysis.
More recently, a phase I clinical trial showed that L-serine is safe for human consumption and that ALS disease progression was slowed by 85 percent (ALSFRS-R scale) at the highest dose tested. The current ALS phase Iia clinical trial at Dartmouth-Hitchcock Medical Center in New Hampshire is seeking to replicate these results.
More recently, a phase I clinical trial showed that L-serine is safe for human consumption and that ALS disease progression was slowed by 85% (ALSFRS-R scale) at the highest dose tested. The current ALS phase Iia clinical trial at Dartmouth-Hitchcock Medical Center in New Hampshire, is seeking to replicate these results.
The Phase 1b portion of the study is currently enrolling patients and is an expansion phase at the highest dose tested in Phase 1a.
Due to the experimental CV75 derived (1546.4 [micro]g/ml), the highest dose tested for lactic acid was 1856 [micro]g/ml and due to solubility limitations, the highest dose tested for 4-aminobenzoic acid was 600 [micro]g/ml.
The highest value of water use efficiency (92.35 kg [ha.sup.-1] [mm.sup.-1]) was obtained by the highest dose tested (300 kg [ha.sup.-1] of [K.sub.2]O), while the potassium use efficiency showed maximum value of 87.41 (kg [ha.sup.-1] [(kg [K.sub.2]O [ha.sup.-1]).sup.-1]) at the optimal dose of 174.29 kg [ha.sup.-1] of [K.sub.2]O.
The highest dose tested promoted very high boron contents, from the first evaluation, carried out 30 days after treatment, reaching the higher content 90 days after treatment with the higher dose, with contents above the toxicity level, which is 200.0 mg [kg.sup.-1] (Malavolta, 2006).
A maximum level (21.5 [micro]M) of malondialdehyde (MDA) production was observed at the highest dose tested compared to (4.95 [micro]M) in the control.
In March 2014, a Phase-1 clinical study in healthy volunteers was completed and no remarkable adverse events were observed, even at the highest dose tested.
According to the company, it expects a 6mg dose to provide for robust efficacy in the treatment of endometriosis and a significant margin of safety compared to the highest dose tested in previous studies, 50mg, based on results of clinical studies.
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