| Acronym | Definition |
|---|
| HDU | Hong Duc University (Vietnam) |
| HDU | High Dependency Unit |
| HDU | Header and Data Unit |
| HDU | High-Density Urethane |
| HDU | Hemodialysis Unit |
| HDU | Himeji Dokkyo University (Japan) |
| HDU | Home Dialyzors United (patient organization) |
| HDU | Human Development Unit (various organizations) |
| HDU | Health Development Unit (UK and Australia) |
| HDU | Hose Drum Unit (air to air refueling) |
| HDU | Helmet Display Unit |
| HDU | Hard Disk Unit |
| HDU | Harley-Davidson University (service school operated by the factory) |
| HDU | Horizontal Drive Unit |
| HDU | How Dare You (Internet slang) |
| HDU | Hot Death Uno (game) |
| HDU | Heat Dissipation Unit |
| HDU | Hose and Drogue Unit (air to air refueling) |
| HDU | Hydraulic Drive Unit |
| HDU | Head-End Distribution Unit |
| HDU | Hazardous Device Unit |
| HDU | Homeless Diversion Unit (New York City) |
