I1AI for 1 Agree
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No significant difference in [DELTA]E* values was observed between the groups I1a, I2a, I3a, S1A, S2a and S3a, which distilled water served as control group (p>0.05).
This study demonstrated that the TNF-[alpha]-induced expressions of CX3CL1 at mRNA and protein levels were also significantly inhibited by Tan I1A in HUVECs.
This study demonstrated that the phosphorylations of NF-[kappa]B and I[kappa]B[alpha] were suppressed by Tan 1IA in a dose-dependent manner, although the degradation of I[kappa]B[alpha] in TNF-[alpha]-stimulated FlUVECs was not prevented by Tan I1A. It may imply that the inhibitory effect of Tan IIA on the phosphorylation of NF-[kappa]B contributes mostly to the inhibited nuclear translocation of NF-[kappa]B.
Diterpene quinone tanshinone I1A selectively inhibits mouse and human cytochrome p4501 A2.
Tanshinone I1A sodium sulfonate protects against car-diotoxicity induced by doxorubicin in vitro and in vivo.
Tanshinone 1, tanshinone I1A, cryptotanshinone were purchased from Chengdu Congon Bio-tech Co., Ltd (China).