IAOIIf and Only If
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The observations were evaluated based on the severity of the ocular response, and the irritation potential of GSE was classified based on the index of acute ocular irritation (IAOI), mean index of ocular irritation (MIOI), and the individual ocular irritation index (IOII) on Day 7.
Regarding ocular irritation, we determined the IAOI of GSE at Day 7 to be 0, classifying it as a non-irritant according to the Draize scoring system (Draize et al., 1944) (Table 2).