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IAP1Inhibitor of Apoptosis 1
IAP1Inhibitor of Apoptosis Protein 1
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In contrast, CAS3 expression was similar under all infection conditions, suggesting that cell death by an extrinsic pathway was inhibited by the IAP because low levels of CAS3 in less-infected oysters were related to high levels of IAP1 and IAP2 (Fig.
We further demonstrate that resveratrol suppressed the expression of various STAT3-regulated gene products, such as antiapoptotic (Bcl-xL, Bd-2, Survivin, and IAP1), proliferative (Cydin D1), metastatic (MMP-2and MMP-9), and angiogenetic (VEGF).
However, the effects of alantolactone on NF-[kappa]B target genes, including IAP1, IAP2, XIAP, cFLIP, survivin, and TRAF1, have not been elucidated yet, while isoalantolactone is not reported yet to affect nuclear factor [kappa]B (NF-[kappa]B) signaling.