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ICAM-1Intercellular Cell Adhesion Molecule Type 1
ICAM-1Intracellular Adhesion Molecule One
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The association between CX3CR1 and integrins through the coexpression of fractalkine/CX3CLl and integrin ligands, such as ICAM-1 and VCAM-1, greatly enhances cell adhesion function more than each system alone.
Soluble ICAM-1 concentrations were measured at the Molecular Epidemiology and Biomarker Research Laboratory in the University of Minnesota, using serum samples diluted 1:400-fold from exam year 15.
Stepwise multiple regression models were used to assess which of the confounding variable could influence hsCRP and ICAM-1.
Conclusion: These results suggest a more dominant role for VCAM-1, but not for ICAM-1 in development of restenosis following coronary stent implantation.
In immunological and inflammatory reactions, ICAM-1 and VCAM-1 are surface glycoproteins that promote adhesion and subsequent recruitment of leukocytes [18].
When hsCRP and ICAM-1 levels were folded into the multivariate adjustment model, metabolic syndrome was no longer associated with a significantly increased risk of PAD, suggesting that systemic inflammation is the driving force in the development of PAD, not the high triglycerides, low HDL, or other components of metabolic syndrome.
61,62,196,197) For example, hydrogen peroxide-induced polymorpho-nuclear neutrophil adhesion is dependent on the rapid induction of the ICAM-1 mRNA signal and the surface expression of ICAM-1 on the endothelial cell.
ICAM-1 normally functions to hold infection-fighting white blood cells in place in regions of the body that have been injured or damaged.
But researchers found a way to trick rhinoviruses with decoy ICAM-1 molecules.
Scientists call this protein ``intracellular adhesion molecule-1,'' or ICAM-1.
Cold viruses not affected by ICAM-1 could be thwarted if receptors are found for them.