We selected 18 candidate genes related to As metabolism (PNP, GSTO1, GSTM1, GSTP1, GSTT1, AS3MT, MTHFR, and CBS), oxidative stress (HMOX1, NOS3, SOD2, and CYBA), and inflammation/endothelial dysfunction (APOE, TNF, IL6, ICAM1, VCAM1, and S1PR1).
The multiplicative interaction between well-water As and 2 SNPs--rs281432 in ICAM1 ([p.
The joint effects for the ICAM1 rs281432 and VCAM1 rs3176867 SNPs considered with dichotomous well-water As are presented in Table 3.
RT-PCR was performed for ICAM1, VCAM1, CCL2, BCL2, BAX and CASP9.
Effects of EGCG and L-theanine on TNF-[alpha]-induced ICAM1, CCL2 and VCAM1 gene expression in cultured endothelial cells
Expression of ICAM1
and VCAM1 serum levels in rheumatoid arthritis clinical activity: association with genetic polymorphisms.
The effect of PCB-153 in precursors was similar to that of AhR ligands for CYP19A1, ICAM1, PTGS2, TNFRSF11B, and VCAM1 and different for CXCL12, MB, IGFBP3, NPTX1, STAT1, THBS1, and WNT5A.
To validate this results, we assessed the modulation of ICAM1 (Brake et al.
This is the first study to report that ICAM1 likely plays a major role in the invasion of cancerous cells and in the growth and metastasis of breast tumors, as announced today by SEQUENOM .
The key findings demonstrated that the level of ICAM1 protein expression on the cell surface positively correlated with metastatic potential of several human breast cancer cell lines and that ICAM1 mRNA levels were elevated in breast tumor compared to normal tissue.
0 Version Featuring On-Demand SFA Synchronization LAM055 05/23/2005 09:01 r f bc-CA-Sequenom-Cancer (SAN DIEGO) SEQUENOM Reports Link Between ICAM1
Gene and Breast Cancer Metastasis NYM012 05/23/2005 09:01 r f bc-NY-Agency.
Finally, the last panel, "Role of ICAM1
in invasion of human breast cancer cells" (Abstract # 2333) will take place on Monday, April 18th at 8:00 a.