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ICAM1Intercellular Cell Adhesion Molecule-1
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In addition, ICAM1 was involved in six KEGG pathways of subnetwork c, such as viral myocarditis, cell adhesion molecules (CAMs), and NF-[kappa]B signaling pathways (Table 2).
Vascular cellular adhesion molecule-1 and ICAM1, (also known as CD54) are adhesion molecules of similar structure and function.
IL-1[beta] and TNF-[alpha] are associated with the increased expression of vascular cell adhesion molecule 1 (VCAM-1) and intercellular cell adhesion molecule 1 (ICAM1) [67].
In a study in cancer-related signalling pathways in EBV-associated GC, genes of cell cycle regulation (IGFBP3, CDKN2A, ID2, HSP70, CCND1, and ID4), DNA repair (BRCA1, TFF1), cell adhesion (ICAM1), angiogenesis (HIF1A), and inflammation (COX2) were found deregulated [200].
We measured the levels of VEGF, MCP-1, IL-6, and ICAM1 in vitreous body at 1,7, and 14 days after laser, following the methods of Arimura et al.
In addition, ICAM1 expression is also upregulated in both type 1 [264] and type 2 [265] models of diabetic nephropathy accompanied by disease progression.
SLAT-transfected Jurkat-TAg cells showed an increase in TCR-induced adhesion to ICAM1 relative to control transfectants, as previously shown [16].
In the context of atherosclerosis in mice, recombinant ANGPTL2 protein promotes inflammation of endothelial cells, the expression of proinflammatory cytokines such as IL6 and TNFa and adhesion molecules such as ICAM1 and P-selectin, and accelerates the formation of the atherosclerotic plaque [50].
These genes are ubiquitin A-52 residue ribosomal protein fusion product 1 (UBA52), ribosomal protein L38 (RPL38), integrin subunit alpha L (ITGAL), intercellular adhesion molecule 1 (ICAM1), interleukin 7 receptor (IL7R), interleukin 7 (IL7), REL protooncogene, NF-KB subunit (REL), NF-KB inhibitor alpha (NFKBIA), Vav guanine nucleotide exchange factor 1 (VAV1), and lymphocyte cytosolic protein 2 (LCP2).
In the intervention group, the serum level of ICAM1 was significantly lower compared to control group, at the end of study (342.7 [+ or -] 16.5 [micro]g/L vs.
(1) IL17 Stimulation of IL-6 and IL-8 production and enhanced ICAM1 expression on human foreskin fibroblasts.