ICDHIso-Citrate DeHydrogenase
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The NADPH-generating enzymes, such as ME, MDH, ICDH, and G6PDH, provide the primary sources for lipogenesis.
FFA, free fatty acid; FAT fatty acid translocase; ACC[alpha], acetyl-CoA carboxylase [alpha]; FAS, fatty acid synthase; ICDH, isocitrate dehydrogenase; G6PDH, glucose 6-phosphate dehydrogenase; MDH, malate dehydrogenase; ME, malic enzyme; TC, triglyceride; CPT1A, carnitine palmitoyl transferase 1A; ATGL, adipose triglyceride lipase; HSL, hormone-sensitive lipase; TCA, tricarboxylic acid cycle; PPP, pentose phosphate pathway; P/C, pyruvate/citrate; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEMT, phosphatidylethanolamine N-methyltransferase; VLDL, low-density lipoprotein.
(11) In the report of High Commission for Planning (2004), municipal human development index (ICDH) is measured by: i) Health situation, measured by the infant mortality rate or the indicator of the level of development of the health sector.
(1946), lactate dehydrogenase (LDH) according to Cabaud and Wroblewski (1958), isocitrate dehydrogenase (ICDH) according to Bell and Baron (1960), glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) according to Reitmann and Frankel (1957), cholinesterase (ChE) according to Rappaport et al.
ICDH, cofilin 1, peroxire-doxin, tubulin a, and TGF[beta]1 which are known for their role in DN, were discussed.
Diminishing activity of NAD: ICDH through repression or significant decrease in intracellular AMP concentration via the activation of AMP deaminase would result in the accumulation of citrate which serves as the precursor for ATP citrate lyase (ACL).
Asn supplementation increased pyruvate kinase (PK), PDH, CS, and isocitrate dehydrogenase (ICDH) p mRNA expression (linear, p<0.05; quadratic, p<0.05), and had a tendency to increase Hexok 2 mRNA expression (linear, 0.05<p <0.1) at 24 h after LPS challenge.
Other enzymes like alkaline phosphatase (AkP), isocitrate dehydrogenase (ICDH), glutamate oxaloacetate transaminase/aspartate aminotransferase (GOT), glutamate pyruvate transaminase/alanine aminotransferase (GPT), trehalase and amylase were found elevated in larvae of OP resistant T.
There were no significant difference in SREBP-2, ME, ICDH, ApoB and FABP2 mRNA expression between Kp-10 treated and control cells (p>0.05).
High activities (43% and 117%) of LDH and isocitrate dehydrogenase (ICDH), respectively, in resistant insects indicates that both catabolic pathways (glycolysis and TCA cycle) are switched on to cope with the insecticidal stress, thus keeping up its ability to resist the insecticide which is obvious by significant decrease (25%) in glucose level.