ICP22

AcronymDefinition
ICP22Infected Cell Protein 22
References in periodicals archive ?
By combining genomic gene deletion, exogenous gene insertion, capsid modification, miRNA modification, promoter and strains selection, Creative Biolabs develops Pre-made Oncolytic Herpes Simplex Virus characterized by superior packaging capacity of >30 kb foreign DNA with low toxicity as an expression vector, avoiding evading the host immune response and reduce toxicity by gene knock-out, such as ICP0, ICP4, ICP22, ICP27 or ICP47.
El gen ICP22 ha sido descrito como transactivador y desempena un papel en la regulacion genica post-transcripcional inhibiendo el Splicing del virus y la celula hospedera (11).