Sillajen, Transgene's partner that is conducting the study, has informed the company of the IDMC
's recommendation to halt enrolment in the study, as it is unlikely to meet its primary objective by the time of the final analysis.
For patients being treated with Rova-T in TAHOE, the IDMC
recommended that investigators and patients make individual decisions as to whether or not to continue treatment based on patient level response.
The agreement was signed by Sheikh Musallam bin Said Qatan, chairman of the Board of Directors of Al Murooj Dairy, with IDMC
The company added an Independent Data Monitoring Committee (IDMC
) recommended stopping enrolment in TAHOE due to shorter overall survival in the Rova-T arm compared with the topotecan control arm.
"Certain countries drop off the international agenda only to reemerge a few years later with significant numbers of new displacements," says Alexandra Bilak, director of IDMC
. 'This was the case for the Democratic Republic of the Congo, which highlights how the failure to address the underlying causes of conflict and crisis results in cyclical patterns of displacement."
The Internal Displacement Monitoring Centre (IDMC
) revealed that 61 per cent of new displacements in 2017 had been triggered by natural disasters, surpassing warfare and political conflict, which contributed to only 39 per cent of mass migration.
This figure, which is attributed to the Internal Displacement Monitoring Centre (IDMC
) accounts for the presence of NGOs in North Eastern Nigeria.
The region accounted for nearly half the 11.8 million people worldwide who were displaced within their countries by conflict last year, according to a report from the Geneva-based Internal Displacement Monitoring Centre (IDMC
Segun el Centro de Seguimiento de los Desplazamientos Internos (International Displacement Monitoring Centre, idmc
), al finalizar 2015 cerca de 8.6 millones de personas fueron obligadas a abandonar sus territorios por causas relacionadas directamente con la guerra, el conflicto armado, la violencia generalizada o las violaciones al derecho internacional humanitario.
The most important report on worldwide internal displacement, by the Internal Displacement Monitoring Centre (IDMC
), states that from 2006 to 2014, at least 481 000 people had been internally displaced in Mexico.
Crisp, (2012), Fitzpatrick (2002) and Internal Displacement Monitoring Centre (IDMC
) affirmed the current status and obstacle facing IDPs in Nigeria recorded that as at 2013, 3.3 million people were displaced in Nigeria essentially as a result of insurgency.
Overall, while AS may be a reasonable option for some IDMC
good- and intermediate-risk patients selected by experienced physicians, more studies are needed to more objectively determine for which patients this would be appropriate.