The 50 ng/ml IFN-a
(Peprotech, America) was added for 12 h as IFN-a
In the current study, we had investigated the polymorphism and phylogenetic analysis of IFN-a
gene in Pakistani indigenous Beetal goat breed.
In another study Hurlock (2001) examined the impact of pre-interferon anxiety in hepatitis C patients and found that IFN-a
therapy worsen the symptoms of pre-existing anxiety21.
One of the most common phenomena after IFN-a
treatment is the appearance of autoantibodies against the thyroid.
Secretion of IFN-a
is one of the most important functions of pDC to simulate immune response.
Secondly, a direct vasospastic effect of IFN-a
is also a possibility.
Methods: The study was carried out on a total of 50 patients of chronic hepatitis C on recombinant IFN-a
Elevated levels of interferon-gamma (IFN-a
), interleukin (IL)-4, and IL-17 produced by T cells have been documented in SLE.,,,
Therefore, we assessed the signature cytokine IL-17 and IFN-a
expressions by CD8[sup]+ T lymphocyte in peripheral blood from patients with COPD and analyzed the difference in the plasticity between Tc17 cells and Th17 cells.
It has been well-characterized that IL-4 and IL-13 expression is increased in acute AD lesions whereas interferon-a (IFN-a
) expression is increased in chronic lesions.[sup], Since the distinctive imbalance of Th1and Th2 immune response exists in AD, we hypothesized that Th1/Th2 cytokines might regulate the proteases involved in FLG metabolic processes.
Since IFN-[beta], but neither IFN-a
nor IFN-[gamma], was induced by poly IC treatment in MCs under the conditions used here [11,12], we conclude that IFN-[beta] is a major player in the TLR3 signaling within MCs [11-14].
IL-17 in MPE were significantly increased when compared with blood, and while IFN-a
showed anti-tumor role, IL-17 probably facilitated the development of tumor.