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This change from the CDC's previous guidance that pregnant women receive a seasonal inactivated influenza vaccine (IIV) was recommended by the Advisory Committee on Immunization Practices after some heated debate among committee members over evidence presented to support the change in wording (MMWR.
seasonal influenza vaccines; 2) information on influenza vaccine products expected to be available for the 2015-16 season; 3) an updated algorithm for determining the appropriate number of doses for children aged 6 months through 8 years; and 4) recommendations for the use of live attenuated influenza vaccine (LAIV) and inactivated influenza vaccine (IIV) when either is available, including removal of the 2014-15 preferential recommendation for LAIV for healthy children aged 2 through 8 years.
With the introduction of the quadrivalent vaccines, "we've had to replace our time-honored TIV abbreviation," replacing the abbreviation for trivalent inactivated vaccine (TIV) with IIV (inactivated influenza vaccine), she said.
The IIV class includes trivalent (1IV3) vaccines (those that are egg based and those that are cell-culture based) and quadrivalent (IIV4) inactivated vaccines.
Among IIVs for which ovalbumin content was disclosed during the 2011-12 through 2013-14 seasons, the reported maximum amounts were [less than or equal to] 1 [micro]g/0.5 mL dose.
Observation spots are available for IIVS' annual training workshop.
In addition to aerosol exposure capabilities, IIVS has developed automated methodologies to deliver nanoliter microdroplets topically onto tissue models in a manner not previously achievable using conventional micropipettor dosing techniques.
Training by IIVS scientists is a key component of a Memorandum of Understanding between the CFDA's National Institute for Food and Drug Control (NIFDC) and IIVS, and is designed to assist the CFDA with the adoption and implementation of non-animal methods.
Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), IIVS has released a technical training video for the In Vitro 3T3 NRU Phototoxicity Assay (OECD TG432).
IIVS Principal Scientist for Respiratory Toxicology, Dr Holger Behrsing, was invited to present at the National Academies of Sciences, Engineering, and Medicine's (NAS) workshop on electronic nicotine delivery systems (ENDS), e-cigarettes.
IIVS presented the following posters at SOT 2017, March 12-16 in Baltimore:
This led to collaboration between the EPA, seven AMCP companies, the Institute for In Vitro Sciences (IIVS), and the Accord Group in 2004.
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- Iius, Belyi and Chernyi