IKKB


Also found in: Medical.
AcronymDefinition
IKKBIntegraal Keten Kwaliteit Beheersysteem (Dutch)
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References in periodicals archive ?
Resumidamente, os mecanismos que explicam este quadro sao a ativacao de quinases, especialmente IkKB e JNK.
Zinc then binds another protein in the NF-kB pathway known as IKKB, which halts further activity, thereby preventing excessive inflammation such as occurs during sepsis.
The objective of this paper was to measure NF-[kappa]B, its inhibitor subunit beta (IKKB), and oxidative stress in the placenta and umbilical cord of pregnant women submitted to a supervised nutritional program, in order to provide a possible explanation of the benefits of limiting gestational weight gain.
Subsequently, IRAK1 and TRAF6 dissociate from the receptor complex and interact with kinases IKKB (IkappaB kinases) resulting in the activation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells), permitting the expression of genes of pro-inflammatory cytokine and chemokines such as TNF-[alpha], IL-6, IL-8 and IL-1[beta](5, 7).
Tai buvo IKKB "NSEL 30 indekso fondas, kuris iki siol yra vienintelis Lietuvoje veikiantis fondas, turintis juridinio asmens statusa, savo valdymo organus--akcininku susirinkima ir stebetoju taryba (OMX Baltic Benchmark Fund prospektas 2011).
They also found that treating mice with normal IKKB activity with small molecule inhibitors of the enzyme could inhibit the growth of melanoma lesions.
The activity of NF-kB is tightly regulated by the IkB kinase complex (IKK), which is composed of two catalytic subunits, IKKa and IKKb, and one regulatory subunit, Nemo/IKKg.