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References in periodicals archive ?
The 18-flurodeoxyglucose positron emission tomography/computed tomography (18 FDG PET-CT) is an alternative method that can be used in the diagnosis of ILD. A recent study evaluating patients with connective tissue disease reported that deep-inspiration breath-hold 18F-FDG-PET/CT could be a useful method in the diagnosis of ILD (15).
In Gabbay et al [10] study, 33% of patients showed evidence of ILD on HRCT with GGO in 28%, reticulations in 39%, honeycombing in 6%, bronchiectasis in 6%, traction bronchiectasis in 6%, consolidation in 3%.
The recent timely and very comprehensive Fleischner Society white paper (1) on the diagnostic criteria of IPF highlights recent advances in our understanding of HRCT imaging in ILDs, and perhaps, importantly, the pitfalls and current gaps in our understanding of the utility of HRCT imaging in predicting histopathology in patients with ILDs.
Interstitial lung diseases (ILDs) are a heterogeneous group of diseases that affect the lung parenchyma.1 They have variable aetiologies, signs and symptoms, radiographic and histologic features.
(6) have reported anti-Jo-1 antibodies in the sera of 25% of PM/DM patients, 7.5% of myositis patients without the complication of ILD, 68% of patients with ILD complication, and 3% of patients with ILD in the absence of myositis.
Immunosuppressive therapy is currently the standard treatment for ILD, although there is little evidence to support this practice.
In this study, we showed that the presence of clubbing in patients with ILD was associated with lower blood oxygenation levels, higher serum KL-6 levels, and lower pulmonary function when compared to those without clubbing, regardless of the underlying etiology of ILD.
The CADM patients with rapidly progressive ILD had specific autoantibodies, originally called anti-melanoma differentiation-associated gene 5 (MDA5) antibody [11].
Diagnosis of ILD can be delayed when clinicians neglect the initial symtoms or attribute them to more commonly encountered lung diseases such as chronic obstructive pulmonary airway disease (COAD).
Recent data published by the ILD Pakistan registry, which collected data from 2010-2016, showed IPF to be the most common ILD (32.9%), followed by sarcoidosis (18.5%).9 In India, a prospective ILD registry found hypersensitivity pneumonitis as the most common ILD (47.35%).10
Thomson is also involved in the management of patients with ILD, also known as idiopathic pulmonary fibrosis or "stiff lungs".