Early diagnosis in leprosy --Comparing diagnostic tests in a large prospetive study (The INFIR
Midwives Gail Wright and Eleanor Smith, who have featured on Channel 4 TV's One Born Every Minute - a fly-on-the-wall series based in Leeds hospitals - were presented with a PS1,000 donation towards their work at Leeds General Infir
Cohort study: assessment of sensory and motor neuropathy in leprosy at baseline.
She is captain of the Primrose Hill Ladies Bowling Team, a member of Newsome Church and its Mothers' Union and she also knits clothes for the premature babies at Huddersfield Royal Infir
The scales chosen were: the prototype of the "Reaction Severity Assessment" (5) developed as part of the ILEP Nerve Function Impairment and Reaction (INFIR
) Cohort Study, (6) the 'modified Ramu' scoring system reported in a controlled trial of thalidomide in Chandigarh, India (7) and a scale described by Haslett et al.
A patient undergoing MPS is given a radioactive tracer injection into the arm and returns the following day where the amount of tracer reaching the heart is imaged at the Trust's specialist unit at Huddersfield Royal Infir
reported that half of the INFIR
cohort without clinical evidence of neuropathy had impaired NCS for the superficial radial and sural nerves.
She died three days later in Huddersfield Royal Infir
A Severity Scale for T1R, based on the INFIR
clinical severity scoring system, was developed and prospectively validated in Bangladesh and Brazil.
cohort study (10) conducted a comparison of diagnostic tests in a sample of only multibacillary patients, and their conclusions showed that the monofilaments and voluntary muscle tests are valid as screening tests.
(18) The INFIR
study reported 38% of patients presented with nerve function impairment (NFI) at the time of registration, out of which 21% had sensory and motor impairment of recent onset treated with steroids.
By 2002, BANDS, (5) AMFES (6) and TRIPOD (7-9) had already greatly added to our understanding of the epidemiology, detection and prevention of nerve impairment and in 2005 results began to be published from the INFIR
study which contributed significantly to our understanding of the order and sequence of effects of neuropathology on sensibility and motor function.