[2,9] Although INH resistance is associated with resistance-conferring mutations in multiple genes, katG and inhA
account for ~90% of resistance detected by phenotypic DST.
This work was supported by a research grant from Inha
University Hospital, Incheon, Korea.
In 106 INH resistant strains, 97(91%) were associated with mutation in katG gene while resistance in 9 (8.4%) strain was due to mutation in the inhA
The organizers of the Women Techmakers IWD are the Google Developer Groups (GDG) Tashkent with the support of Inha
University in Tashkent, the joint project of Ministry for Development of Information Technologies and Communications of Uzbekistan and UNDP project "Public Administration Reforms and Digital Transformation" and Super Dispatch.
These results preliminarily showed that G841A of the INHA
gene was a potential marker for improving litter size in goats.
To find out mutations in isoniazid-resistant isolates, 30 isolates were randomly selected for amplification of katG and inhA
genes using primers described by Telanti et al.17 A 209 bp fragment of katG and 248 bp fragment of inhA
genes were amplified in a thermal cycler [Eppendorf AG 22331 Hamburg].
Patterns of Amino Acid Changes and Mutations in inhA
The four mutations probes for the inhA
gene detected mutations at the codons C15T (inhA
MUT1), A16G (inhA
MUT2), T8C (inhA
MUT3A) and T8A (inhA
Frequency of polymorphisms in katG, inhA
and rpoB genes and their association with drug resistance
The Rmut primer is a reverse primer that binds to the nucleotide +5 to -15 inhA
promoter region in mutant strains and creates a 174 bp band with TB92.
Cette premiere exposition dediee a la cartographie, ouverte au public du 20 janvier au 2 mai prochain, est organisee en collaboration avec l'Institut national d'histoire de l'art (INHA
) et la Bibliotheque nationale de France (BNF) avec le soutien du ministere francais de la Culture, annonce-t-on sur le site Internet du MuCEM.