IPEH is an uncommon benign vascular disease of the skin and the subcutaneous tissue with abundant endothelial proliferations in normal blood vessels.
IPEH mostly occurs in the 5th decade of life and there is no gender or age predilection, although some studies have suggested that it is more common in women than in men.
The diagnosis of angiosarcoma can be a challenge due to pathohistologic features mimicking IPEH (Masson's tumour) as seen in the current case.
Immunohistochemical staining for endothelial markers, such as CD31 and CD34, can be used to differentiate IPEH from non-vascular lesions.
Several members of the Ampatuan clan, including Ipeh
s father and grand father, are also in custody while being tried for the murders.
. Instituto Peruano del Esparrago y Hortalizas.
Histopathologic examination of the mass revealed IPEH (figure 3).
IPEH is a relatively rare lesion that occurs in the fingers, head and neck, trunk, lower extremities, and upper extremities, in order of decreasing frequency.
Recent research has also supported the reactive nature of this lesion,[2,3] and IPEH was the most commonly used term. Intravascular papillary endothelial hyperplasia was most frequent in the dermis and subcutis of the head and neck regions and in the lip, tongue, and buccal mucosa.[2,7] Rare locations included the thyroid, orbit, parotid gland, masseter muscle, nose, mandible, pharynx, and central nervous systern.[3,8]
To our knowledge, only 2 cases of IPEH in the maxillary sinus have been reported.[4,5] Clinically, the present case was similar to the previously reported case of the maxillary sinus lesion that extended to the ethmoid sinus and nasal cavity and compressed the floor of the orbit, causing pain and unilateral proptosis. This article describes the first case to our knowledge of ethmoid sinus IPEH, differing from the previously published IPEH of the maxillary sinus[4,5] in that the lesion was associated with a vascular lesion and expanded into the adjacent sphenoid sinus and sellar region.
Although it is ubiquitous in nature,  IPEH has a predilection for the head and neck region.
In this article, we report the case of a patient who had an IPEH deep within the soft tissues of the neck, which manifested as a lateral neck mass.