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IPSIDImmunoproliferative Small Intestinal Disease
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Considered a variant of MALT lymphoma with nearly complete plasmacytic differentiation, IPSID is a rare disorder.
Just as gastric MALT lymphomas are known to be related to infection with H pylori, IPSID is suspected to result from Campylobacter infection, and early cases have a relatively high rate of response to broad-spectrum antibiotics.
Immunoproliferative small intestinal disease (IPSID), formerly known as Mediterranean lymphoma or [alpha] heavy chain disease, is an uncommon and unusual type of gastrointestinal lymphoma that is included under the umbrella of MALT lymphoma in the current WHO classification scheme.