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IRF2Interferon Response Factor 2
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Across species, the intron hmgn2 (mean length of 347 nt) had a mean of 15.4 haplotypes and 17.4 polymorphic sites; irf2 (540 nt) averaged 12.2 haplotypes and 15.5 polymorphic sites; mb (689 nt) had the smallest number of haplotypes (7.4) and polymorphic sites (6.5); nat15 (528 nt) had a mean of 14.1 haplotypes and 17.5 polymorphic sites; pcbd (538 nt) had the highest mean number of haplotypes (15.7) and polymorphic sites (19.5); and finally, rho (434 nt) had a mean of 9.7 haplotypes and 9.6 polymorphic sites.
1 MS (PP) NA Inflammation 14 0 Ctrl related mechanisms (Chemokine receptor [up arrow], TNF-[alpha] R2 [up arrow], IRF2 [up arrow]) 2 MS (PP, RR) NA Biosynthesis of 18 3 Ctrl (pooled) pro- inflammatory leukotrienes (5-lipoxygenase [up arrow]) 4 MS (SP) NA IgFcR 22 [up arrow] in inactive 2 Ctrl lesions, G-CSF [up arrow] in active lesions.
In mammals the IRF gene family consists of nine members: IRF-1, IRF2, IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, IRF-8/ICSBP, and IRF-9.
(2002) detected the expression of the mouse IRF2 mRNA in several tissues by RT-PCR and also found higher expression levels in lung, liver and much lower expression levels in brain, heart, which is consistent with our results in pigs.