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IRS-2Insulin Receptor Substrate-2 (protein)
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References in periodicals archive ?
Mice without IRS-2 start life with fewer beta cells than normal mice, the researchers found.
It's not clear what role IRS-2 plays in beta cells or even if it acts there only in response to insulin.
Other diabetes researchers remain skeptical that IRS-2 plays a major role in the human illness, noting that White and his colleagues have so far failed to unearth people with diabetes who have flaws in the gene for IRS-2.