IRTXInfra Red Module Data Transmit
Copyright 1988-2018, All rights reserved.
References in periodicals archive ?
Fluorescence was measured at 510 nm emission, with excitation wavelengths of 340 and 380 nm, at baseline and after stimulation with capsaicin either with or without pretreatment with iRTX (1 [micro]M) for 5 min.
Cells were treated with capsaicin (100 nM) in the presence or absence of iRTX (1 [micro]M) for 24 h before total protein was extracted.
Inhibition of TRPV1 by a specific blockade named 5,-iodo-resiniferatoxin (iRTX) prevented the capsaicin-induced [[Ca.sup.2+]] increase.
To better understand the possible molecular mechanisms for activation of TRPVl by capsaicin which upregulates PPAR-[delta] expression, we detected the protein changes in the cultured H9c2 cells stimulated by capsaicin and iRTX. As shown in Figure 5, the protein expression of PPAR-[delta] was increased in the capsaicin group compared to control group (P < 0.01), which was partially reduced by iRTX treatment (P < 0.05).
5,-Iodoresiniferatoxin (IRTX) was purchased from Tocris Cookson (Ellisville, MO).