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The study of immunostimulating activity showed the low adjuvant activity of phospholipid (phosphatidylcholine) ISCOM and MGDG-ISCOM for OmpF-like porin from enteropathogen Yersinia pseudotuberculosis (YOmpF) .
Abbreviations CD: Sum of monosulfated triterpene glycosides from Cucumaria japonica CDA: Cucumarioside [A.sub.2]-2 CDG: Cucumarioside G DGDG: Digalactosyldiacylglycerol FRA: Frondoside A GM-CSF: Granulocyte-macrophage colony-stimulating factor HTA: Holotoxin [A.sub.1] HSA: Human serum albumin ISCOM: Immunostimulating complex ISCOMATRIX: Matrix of immunostimulating complex MGDG: Monogalactosyldiacylglycerol PUFA: Polyunsaturated fatty acid Quil A: Mixture of triterpene glycosides extracted from the bark of Quillaja saponaria SQDG: Sulfoquinovosyldiacylglycerol Th1: T helper cells of type 1 Th2: T helper cells of type 2 TI-complex: Tubular immunostimulating complex HA0: Recombinant uncleaved hemagglutinin monomer YOmpF: OmpF porin from Yersinia pseudotuberculosis.
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