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The results of our analysis showed that IVGC + OR had the highest probability to be the best treatment in terms of response rate, follow by teprotumumab and IVGC.
Recent published meta-analysis comparing common immunosuppressive therapies for TED concluded that IVGC is an effective treatment and has a significant advantage over OGC with fewer adverse events [6, 8].
It is necessary to mention that comparing OIGC directly with systemic glucocorticoids undermines the specific efficacy of this treatment which may be indicated following IVGC patients with unbearable side effects or in recurrences.
Our results indicating that IVGC + OR ranked the best in terms of response rate supported these findings.
but was slightly better than IVGC in the second study by Salvi et al.
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