IVIVC

AcronymDefinition
IVIVCIn Vitro in Vivo Correlation (UK)
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References in periodicals archive ?
However, the deuterium role in complex biological systems has not been fully established, which requires further studies in the IVIVC system.
In Vitro Study of Deuterium Effect on Biological Properties of Human Cultured Adipose-Derived Stem Cells
Various IVIVC studies have been published for a number of formulations, including Busprion, propranolol, nevirapine, metoprolol and other drugs.
Development, Internal and External Validation of Naproxen Sodium Sustained Release Formulation: an Level A In Vitro-In Vivo Correlation/Naproksen Sodyum Sureli Serbest Formulasyonun Gelistirilmesi, Ic ve Dis Olarak Dogrulamasi: Bir Duzey A In Vitro-In Vivo Korelasyon
IVIVC is a biopharmaceutical tool used in drug development and formulation optimization to demonstrate that equivalence.
Modeling & simulation for drug development & formulation: a look at how to leverage modeling and simulation technology to enhance all phases of the drug development process
Caption: FIGURE 10: Linear regression multiple-level C IVIVC correlation models for (a) Madopar HBS capsules; (b) PXLNET matrices; and (c) IPB matrices.
Ex Vivo and In Vivo Characterization of Interpolymeric Blend/Nanoenabled Gastroretentive Levodopa Delivery Systems
Thus, in principle, the establishment of in vitro-in vivo correlations (IVIVCs), whereby the dissolution rate may serve as a surrogate for systemic exposure (e.g., bioavailability, "area under the curve" (AUC), or [C.sub.max]), is highly desirable because it could reduce the number of BE studies required for generic drug product development and registration (4).
Innovative in vitro methodologies for establishing therapeutic equivalence/Metodos in vitro innovadores para determinar la equivalencia terapeutica
The RA values were used to determine the IVIVC between liver damage and the assays.
Mechanism profiling of hepatotoxicity caused by oxidative stress using antioxidant response element reporter gene assay models and big data
En este estudio se logro el proposito de implementar metodologias analiticas, que habitualmente se aplican en la investigacion y desarrollo de nuevos farmacos, para medir propiedades fisicas y biologicas, con resultados coherentes con los obtenidos en los estudios de Biodisponibilidad en sujetos humanos, acordes con los principios de una IVIVC. En todas las comparaciones se demostraron valores de regresion lineal por minimos cuadrados con factores de correlacion cercanos o superiores 0.90, en la combinacion de comparaciones como:
Modelo de correlacion farmacocinetico in vitro-in vivo para el aseguramiento de la calidad de medicamentos antirretrovirales
Statistical moment analysis is applied to determine level B IVIVC. In this level of correlation, the mean in-vitro dissolution time (MDT vitro) of the product is compared to either mean in-vivo residence time (MRT) or the mean in-vivo dissolution time (MDT vivo).
A systematic approach to develop level A, in-vitro and in-vivo correlation (IVIVC)-ketoprofen BCS Class II drug example
Pathak, "Wet process-induced phase-transited drug delivery system: a means for achieving osmotic, controlled, and level A IVIVC for poorly water-soluble drug," Drug Development and Industrial Pharmacy, vol.
Development and optimization of osmotically controlled asymmetric membrane capsules for delivery of solid dispersion of lycopene
Establishing an IVIVC (in vitro in vivo correlation) remains a challenge for non-oral dosage forms like long acting injectables.
IVIVC from Long Acting Olanzapine Microspheres
Gupta, "In vitroin vivo correlation (IVIVC) study of leflunomide loaded microspheres,' International Journal of Pharmacy and Pharmaceutical Sciences, vol.
Application of liposomes in treatment of rheumatoid arthritis: quo vadis
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