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IP3Inositol Triphosphate
IP3Third Order Intercept Point
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References in periodicals archive ?
PLC[gamma]1 is an enzyme which upon phosphorylation to its active form cleaves the membrane phospholipid, phosphatidylinositol 4, 5 biphosphate (PIP2) to diacylglycerol (DAG) and inositol triphosphate (IP3), which regulate intracellular calcium stores and protein kinase C levels (2).
Preconditioning causes the activation of various receptors (adenosine A1 receptors, opioid receptors and bradykinin receptors) and the generation of other free radicals, which then transmit signals via G proteins, which lead to the formation of inositol triphosphate, production of diacylglycerol and cause the activation of protein kinases, phosphorylation of ADP and the enhancement of [K.sub.ATP] channel opening.
Parker I, Miledi R (1986) Changes in intracellular calcium and in membrane currents evoked by injection of inositol triphosphate in to Xenopus oocytes.