(redirected from Intention-To-Treat)
ITTInitial Teacher Training (UK)
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ITTI Think That
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References in periodicals archive ?
Among the 778 AFib patients enrolled in CABANA with any form of HF (35% of the total study enrollment), the incidence of the study's primary endpoint--the combined rate of death, disabling stroke, serious bleeding, or cardiac arrest during a median follow-up of slightly more than 4 years--was 36% lower among the catheter-ablated HF patients than in the HF patients assigned to medical treatment, according to an intention-to-treat analysis, which was a statistically significant difference.
The investigators planned both an intention-to-treat and a per-protocol analysis in their registered clinical trial.
Using intention-to-treat analysis, the mean number of days with headache was 18.5 with placebo and 13.6 with candesartan (P=.001).
All safety analyses were conducted according to intention-to-treat. Gastrointestinal bleedings, which were mostly mild, occurred in 61 (0.97%) individuals in the aspirin group versus 29 (0.46%) in the placebo group (HR 2.11, 95% CI 1.36-3.28, p=0.0007).
There was no difference between sex in reducing distal colorectal cancer either in the intention-to-treat analysis (42% for men vs 40% for women) or in the per-protocol analysis (56% for men and women).
By intention-to-treat analysis 15% were in the treatment group vs.
When the changes in blood pressure during the study period were compared between study groups by intention-to-treat, the CPAP group achieved a 3.1 mm Hg greater decrease in 24-hour average blood pressure and 3.2 mm Hg greater decrease in 24-hour diastolic blood pressure, but the difference in change in 24-hour systolic blood pressure was not statistically significant compared to the control group.
An intention-to-treat analysis ("last observation carried forward" method) was used with a Student's t-test for normally distributed variables.
However, the intention-to-treat analysis principle applied in clinical trials in order to avoid bias associated with exposed subjects who withdraw from treatment indicates that former drinkers should in fact be added back to a drinking category based on their previous alcohol consumption pattern [15].
Intention-to-treat analysis showed no evidence for a difference in hip function between treatment groups at 12 months; 95% of follow-up data was available for analysis.
In an intention-to-treat analysis, the prevalences of high risk HPV among the intervention and control groups were 14.8% (94/637) and 22.3% (140/627), respectively, with a prevalence risk ratio of 0.66 (p=0.002).