Indeed, 60% of patients randomized to physical therapy were Kellgren-Lawrence scale grade III-IV versus 45% of those assigned to intra-articular corticosteroid injection
Godwin et al9 in asystematic review concluded that intra-articular corticosteroid injection
results in clinically and statistically significant reduction in pain of OA knee 1 week after injection.
To sum up, following an intra-articular corticosteroid injection
, relief of symptoms, improvement of spatiotemporal gait parameters, and increase of daily physical activity were observed.
They explained the cause of osteonecrosis as a result of repeated intra-articular corticosteroid injections
in the same joints.
Intra-articular corticosteroid injection
for the treatment of idiopathic adhesive capsulitis of the shoulder.
Although the AAOS group has found inconclusive evidence to support the intra-articular corticosteroid injections
, we use this as a means of reducing patients' pain, particularly those patients with an acute exacerbation of their chronic knee OA pain.
Adhesive capsulitis of the shoulder: a systematic review of the effectiveness of intra-articular corticosteroid injections
. J Bone Joint Surg Am 2011;93(18):1727-1733.
Troum of the University of Southern California in Los Angeles highlighted key developments in osteoarthritis during the past year, including two major studies on total knee replacement, the Food and Drug Administration's updated stronger warning on the cardiac and stroke risks of NSAIDs, a randomized trial that effectively takes hydroxychloroquine (Plaquenil) off the treatment menu for hand osteoarthritis, and a reassuring report on the safety of repeated intra-articular corticosteroid injections
in patients with synovitic knee osteoarthritis.
The intra-articular corticosteroid injections
were administered into 30 patients, including 22 female and 08 male, followed by a 2 weeks physical rehabilitation program.
Conditional recommendations included one of the following: acetaminophen, oral NSAIDs, topical NSAIDs, tramadol, or intra-articular corticosteroid injections
. Conditional recommendations were made to not use chondroitin sulfate, glucosamine, or topical capsaicin.
As with knee OA, conditional pharmacologic recommendations for hip OA include one of either acetaminophen, oral NSAIDs, tramadol, or intra-articular corticosteroid injections
Also, chondroitin sulfate and glucosamine were conditionally recommended against.
Patients with early rheumatoid arthritis who were on methotrexate and received intra-articular corticosteroid injections
into inflamed metacarpophalangeal joints for 3 months lost less periarticular density than did those who received methotrexate alone, results from a small study demonstrated.