(redirected from Intracranial Germ Cell Tumor)
IGCTIntegrated Gate Commutated Thyristor
IGCTIntracranial Germ Cell Tumor (brain cancer)
IGCTIntratubular Germ Cell Tumor (cancer)
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Primary intracranial germ cell tumors (GCTs) are 3.1% of all primary brain tumors [1]; they affect pediatric population (mean age of 16.1 years) with a male:female ratio of 4:1 and are located in midline structures such as suprasellar and/or pineal region [2]; tumors contemporary located at suprasellar and pineal regions called synchronous GCT are 13% of all GCTs; these lesions are germinoma (60-80% of patients) with high sensitivity to radiotherapy [3], teratoma (18%), endodermal sinus tumors (7%), embryonal carcinomas (5%), and choriocarcinomas (5%).
Takakura et al., "Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases," Journal of Neurosurgery, vol.
Funada et al., "CT and MRI features of intracranial germ cell tumors," Journal of NeuroOncology, vol.
Primary intracranial germ cell tumors are neoplasms that predominantly occur within the pediatric population and account for 0-4-3.4% of primary intracranial tumors [7].
Ross, "Incidence of intracranial germ cell tumors by race in the United States, 1992-2010," Journal of Neuro-Oncology, vol.
Diez et al., "Primary chemotherapy for intracranial germ cell tumors: Results of the third international CNS germ cell tumor study," Pediatric Blood & Cancer, vol.
Intracranial teratomas account for approximately 0.3-0.9% of all brain tumors and mimic other intracranial germ cell tumors in their tendency to present in midline sites, like the pineal gland and suprasellar regions [4, 6].
Most intracranial germ cell tumors arise in structures around the third ventricle, most commonly in the pineal gland or suprasellar region.
Intracranial germ cell tumors are more common in the postpubertal child and younger adult, with the anatomic location as described above.
Intracranial germ cell tumors: pathobiological and immunohistochemical aspects of 70 cases.
Intracranial germ cell tumors account for 0.4%-3.4% of all brain tumors (1).
Intracranial germ cell tumors. Oncologist 2000;5:312-20.
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