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Related to Intravascular large B-cell lymphoma: Primary effusion lymphoma
ILBCLIntravascular Large B-Cell Lymphoma
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Intravascular large B-cell lymphoma has no specific chromosomal alterations, but many abnormalities reported in other B-cell lymphomas may be seen in IVLBCL.
Intravascular large B-cell lymphoma cells have been demonstrated to lack cell surface proteins critical to lymphocyte transvascular migration, including CD29 ([beta]1 integrin) and CD54 (ICAM-1 or CD11a ligand).
Intravascular large B-cell lymphoma cells irregularly express several immature and mature B-cell antigens, and may be of a germinal center (20%) or nongerminal center (80%) B-cell immunophenotype.
Intravascular large B-cell lymphoma associated with a near-tetraploid karyotype, rearrangement of BCL6, and a t(11; 14)(q13;q32).
Asian variant of CD5+ intravascular large B-cell lymphoma with splenic infarction.
Intravascular large B-cell lymphoma is an uncommon lymphoid neoplasm, which has been alternatively designated as angiotropic large cell lymphoma, intravascular lymphomatosis, or malignant angioendotheliosis.
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