Reoperative sentinel lymph node biopsy: a new frontier in the management of ipsilateral breast tumor recurrence
. Ann Surg Oncol 2007; 14: 2209-2214.
(1) Despite those limitations, however, in the current era of multimodality therapy for women with invasive breast cancer, ipsilateral breast tumor recurrence rates are remarkably low.
Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five National Surgical Adjuvant Breast and Bowel Project protocols of node-negative breast cancer.
An important incidence of ipsilateral breast tumor recurrence (IBTR) for stage 0, I and II patients following BCT.
During the serial follow up of cases, in first 6 months, there was one recurrence ipsilateral breast tumor recurrence (IBTR) noted, probably reason for which was too close margin during resection and patient didn't take radiotherapy there was no recurrence noted in next 6 months.
Effect of margins on ipsilateral breast tumor recurrence
after breast conservation therapy for lymph node-negative breast carcinoma.
Five-year estimates for ipsilateral breast tumor recurrence (IBTR) in 300 patients were notably lower (1.7%) than in contemporary clinical trials, prompting the hypothesis that an IORT boost might be superior to an EBRT boost .
Abbreviations ASTRO: American Society for Radiation Oncology BCT: Breast conservation therapy EBRT: External beam radiotherapy ELIOT: Intraoperative radiotherapy versus external radiotherapy for early breast cancer trial GEC-ESTRO: Groupe Europeen de Curietherapie and the European Society for Radiotherapy and Oncology Gy: Gray IBTR: Ipsilateral breast tumor recurrence IORT: Intraoperative radiotherapy kV: Kilovoltage LR: Local recurrences PB: Partial breast irradiation PM: Partial mastectomy QOL: Quality of life RT: Radiotherapy TARGIT: Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer trial.
Ipsilateral breast tumor recurrence
(IBTR) was defined as recurrence of the cancer in the treated breast.
A variety of patient, treatment, and pathologic factors are associated with an increased risk of ipsilateral breast tumor recurrence
(local recurrence) after breast conservation therapy for invasive breast cancer.
Fisher's landmark NSABP B-06 study  showed at twenty-year follow-up a significant decrease in ipsilateral breast tumor recurrence
from 39.2% to 14.3% (P < 0.001) when lumpectomy patients were treated postoperatively with whole breast irradiation.
Long-term outcomes of invasive ipsilateral breast tumor recurrences
after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS.