JECFAJoint Expert Committee for Food Additives (UN Food and Agriculture Organization and World Health Organization)
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In the case of furfural (non-genotoxic), the EDI has also indicated no health risk, since EDI was lower than the ADI established by JECFA (2000).
It is noted that all individual concentrations and average concentrations exceed the limit established for iron according to JECFA - Joint FAO / WHO Expert Committee on Food Additives, which is 15 ppm for leafy vegetables.
First, the Joint Food and Agriculture Organization (FAO) and WHO Expert Committee on Food Additives (JECFA) established a methylmercury hair-to-blood ratio of 250 that is now commonly used by the research community (JECFA 2004).
The related compound, 4-hydroxy-2,5-dimethylfuran-3(2H)-one (HDMF), which had been evaluated by JECFA in 2004 in a 2-year carcinogenicity study, was considered as the representative compound for this group, and in vitro and in vivo testing conducted for this structurally similar chemical, HDMF, provided sufficient information to rule out genotoxic concern for 4-HMF.
The EDI values for lead were below the PTWI and/or TDI established by JECFA. Similar findings were investigated from the most consumed infant formulas in Europe, where the average PTWI for lead was 2.6 and 5.8 [micro]g/kgbw/week for infants during the formula feeding (0-4 months) and weaning period (5-9 months), respectively [16].
The evaluation of risk assessments of aflatoxins by international bodies has been based on the carcinogenic potencies developed by JECFA, but, recently, the EC Scientific Panel on Contaminants in the Food Chain [32] developed a benchmark dose (BMD) approach.
The EDI for the majority of the analysed samples was found to be within the accepted daily intake (ADI) of 0-0.07 and 0-3.7 mg/kg body weight/day for NI and NA, respectively, which was adopted by Scientific Committee on Food (SCF) and JECFA [31].
(7.) JECFA (Joint FAO/WHO Expert Committee on Food Additives), Summary and conclusions of the sixty-first meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), 2003; 18-22.
The levels of heavy metal were higher than the maximum acceptable limits s reported by JECFA, in both exposed and control goats (2010).