JWCIJohn Wayne Cancer Institute
JWCIJournal of the Warburg and Courtauld Institutes
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Moving forward, Go said the JWCI plans to reach out to more sick people so they can experience the benefits of the VMA Cellular Functional Water technology.
Over the past several years, research at JWCI's Breast Cancer Research Program, under the direction of Myles C.
This latter pathway became a focus of interest several years ago in the JWCI Experimental Therapeutics Laboratory, directed by Dr.
In the 1990s, Cabot and his collaborators at JWCI found that levels of CC were unusually high in breast carcinoma cells resistant to Adriamycin, the world's most widely employed cancer drug.
In targeting ceramide, the JWCI researchers had found a clue to the problem of drug resistance hiding in an unremarkable, yet apparently critical, cellular mechanism.
Yates, "Elizabethan Chivalry: The Romance of the Accession Day Tilts," JWCI, 20 (1957): 4-25, rpt.
Seventeen melanoma cell lines (MA, MB, MC, MD, ME, MF, MG, MH, MI, MJ, MK, ML, MM, MN, MO, MP, and MQ) were established and characterized at the John Wayne Cancer Institute (JWCI).
Blood was drawn from 94 melanoma patients (20 with stage I, 20 with stage II, 32 with stage III, and 22 with stage IV disease) immediately before they received any treatment at JWCI. All patients signed consents for the use of their blood specimens, and the study was carried out according to the guidelines set forth by the Saint John's Health Center and the JWCI Institutional Review Board committee.
[5] Nonstandard abbreviations: AJCC, American Joint Committee on Cancer; RT-PCR, reverse transcription-PCR; PBL, peripheral blood leukocyte; qRT, quantitative real-time reverse transcription-PCR; MART-1, melanoma antigen recognized by T cells-1; GalNAc-T, [beta]1 [right arrow] 4-N-acetylgalactosaminyltransferase; PAX-3, paired box homeotic gene transcription factor 3; MACE-A3, melanoma antigen gene-A3 family; SLN, sentinel lymph node; JWCI, John Wayne Cancer Institute; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; and Ct, threshold cycle.
In addition, other cell lines established and characterized at the John Wayne Cancer Institute (JWCI) were used: breast cancer cell lines JM992Br and PM277Br; CRC cell lines JWCI-0361, JWCI-0427, and JWCI-1100; and melanoma cell lines Matt, M10, M12, M14, M15, M24, M101, M111, and M112.
Pathology-verified primary or metastatic lesions from cancer patients undergoing elective surgeries at the JWCI clinics were used.
Blood samples from cancer patients were collected as described previously from the JWCI Clinic and the Martin Luther King, Jr./Drew Medical Center, Breast Cancer Clinic (Los Angeles, CA) (10, 27).